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Compiled from SEC Form N-PX filings and PRAXIS PRECISION MEDICINES INC.’s Form 8-K, filed June 27, 2025 (Item 5.07 on EDGAR). Page generated October 18, 2026.
Meeting of June 26, 2025: 4 items on PRAXIS PRECISION MEDICINES INC.’s Form 8-K, filed June 27, 2025: 2 approved · 2 without a stated outcome.
Material dissent: a director nominee under 80% of the votes cast, say-on-pay under 70%, any other item the board put forward under 80%, or a shareholder proposal with more than 50%, on the company’s own Form 8-K tally. How this is decided
Proxy season: 2024-2025 2025-2026
Explore PRAXIS PRECISION MEDICINES INC. in the interactive database Compare manager voting policies
These tallies are PRAXIS PRECISION MEDICINES INC.’s own, as disclosed to the U.S. Securities and Exchange Commission on Form 8-K, filed June 27, 2025 (Item 5.07, “Submission of Matters to a Vote of Security Holders”). They cover every share voted at the meeting, not just the funds that file Form N-PX.
| Ballot item | For | Against | Abstain | Withheld | Broker non-votes | Support (of votes cast) | Reported outcome | Voting standard |
|---|---|---|---|---|---|---|---|---|
| Elect Director: Jeffrey Chodakewitz, M.D. | 14,596,188 | -- | -- | 2,998,186 | 778,152 | 83% | Not verified | — |
| Elect Director: Merit Cudkowicz, M.D. | 17,499,300 | -- | -- | 95,074 | 778,152 | 99.4% | Not verified | — |
| 2. Ratification of Appointment of Ernst & Young LLP as the Company's Independent Registered Public Accounting Firm | 18,358,636 | 7,630 | 6,260 | -- | 0 | 99.9% | Approved | — |
| 3. Advisory Vote on Executive Compensation | 10,671,320 | 6,919,705 | 3,349 | -- | 778,152 | 61% | Approved | — |
Source: PRAXIS PRECISION MEDICINES INC., Form 8-K, filed with the SEC on June 27, 2025 — read the filing on EDGAR.
Each item below shows how the 188 asset managers that disclosed a PRAXIS PRECISION MEDICINES INC. vote in their SEC Form N-PX filings actually voted. Share totals are the shares those managers' funds voted, summed across every fund they report.
Combines 3 wordings of this item as funds reported it.
83% Majority: yes · of votes cast
Description as filed by funds: To elect the Class II Directors to serve until the 2028 Annual Meeting of Stockholders and until their respective successors have been duly elected and qualified: Jeffrey Chodakewitz, M.D.
PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“Elect Director: Jeffrey Chodakewitz, M.D.”): 14,596,188 for, 2,998,186 withheld, per its Form 8-K filed June 27, 2025 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.
Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 83% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.
The 51 asset managers below reported 3,712,298 for, 477,120 withheld.
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| Vanguard | 1,053,731 | 0 | 0 | 0 | For |
| T. Rowe Price | 905,205 | 0 | 0 | 0 | For |
| BlackRock | 452,758 | 0 | 0 | 0 | For |
| Fidelity | 361,398 | 0 | 0 | 35,869 | Mixed |
| State Street | 276,907 | 0 | 0 | 353 | For |
| JANUS INVESTMENT FUND | 234,406 | 0 | 0 | 0 | For |
| Aberdeen | 0 | 0 | 0 | 150,691 | Withhold |
| Charles Schwab | 142,945 | 0 | 0 | 0 | For |
| FRANKLIN STRATEGIC SERIES | 0 | 0 | 0 | 113,704 | Withhold |
| Northern Trust | 0 | 0 | 0 | 62,824 | Withhold |
| Equitable | 35,437 | 0 | 0 | 18,040 | Mixed |
| DRIEHAUS MUTUAL FUNDS | 44,110 | 0 | 0 | 0 | For |
| TIAA | 43,460 | 0 | 0 | 0 | For |
| Brighthouse | 35,092 | 0 | 0 | 7,922 | Mixed |
| QUANTITATIVE MASTER SERIES LLC | 25,976 | 0 | 0 | 0 | For |
| Transamerica | 20,311 | 0 | 0 | 0 | For |
| RBB FUND, INC. | 19,393 | 0 | 0 | 0 | For |
| ALPS ETF Trust | 0 | 0 | 0 | 14,808 | Withhold |
| Lincoln Financial | 12,800 | 0 | 0 | 0 | For |
| John Hancock | 5,832 | 0 | 0 | 6,137 | Mixed |
| Direxion Shares ETF Trust | 0 | 0 | 0 | 11,037 | Withhold |
| HUSSMAN INVESTMENT TRUST | 10,500 | 0 | 0 | 0 | For |
| Global X | 0 | 0 | 0 | 10,448 | Withhold |
| UBS | 0 | 0 | 0 | 10,400 | Withhold |
| Brinker Capital Destinations Trust | 10,256 | 0 | 0 | 0 | For |
Showing the 25 largest of 51 asset managers. See all 51 in the interactive database.
Combines 3 wordings of this item as funds reported it.
99.4% Majority: yes · of votes cast
Description as filed by funds: To elect the Class II Directors to serve until the 2028 Annual Meeting of Stockholders and until their respective successors have been duly elected and qualified: Merit Cudkowicz, M.D.
PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“Elect Director: Merit Cudkowicz, M.D.”): 17,499,300 for, 95,074 withheld, per its Form 8-K filed June 27, 2025 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.
Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 99.4% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.
The 51 asset managers below reported 4,150,190 for, 39,228 withheld.
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| Vanguard | 1,053,731 | 0 | 0 | 0 | For |
| T. Rowe Price | 905,205 | 0 | 0 | 0 | For |
| BlackRock | 452,758 | 0 | 0 | 0 | For |
| Fidelity | 361,398 | 0 | 0 | 35,869 | Mixed |
| State Street | 277,260 | 0 | 0 | 0 | For |
| JANUS INVESTMENT FUND | 234,406 | 0 | 0 | 0 | For |
| Aberdeen | 150,691 | 0 | 0 | 0 | For |
| Charles Schwab | 142,945 | 0 | 0 | 0 | For |
| FRANKLIN STRATEGIC SERIES | 113,704 | 0 | 0 | 0 | For |
| Northern Trust | 62,824 | 0 | 0 | 0 | For |
| Equitable | 53,477 | 0 | 0 | 0 | For |
| DRIEHAUS MUTUAL FUNDS | 44,110 | 0 | 0 | 0 | For |
| TIAA | 43,460 | 0 | 0 | 0 | For |
| Brighthouse | 41,344 | 0 | 0 | 1,670 | For |
| QUANTITATIVE MASTER SERIES LLC | 25,976 | 0 | 0 | 0 | For |
| Transamerica | 20,311 | 0 | 0 | 0 | For |
| RBB FUND, INC. | 19,393 | 0 | 0 | 0 | For |
| ALPS ETF Trust | 14,808 | 0 | 0 | 0 | For |
| Lincoln Financial | 12,800 | 0 | 0 | 0 | For |
| John Hancock | 11,969 | 0 | 0 | 0 | For |
| Direxion Shares ETF Trust | 11,037 | 0 | 0 | 0 | For |
| HUSSMAN INVESTMENT TRUST | 10,500 | 0 | 0 | 0 | For |
| Global X | 10,448 | 0 | 0 | 0 | For |
| UBS | 10,400 | 0 | 0 | 0 | For |
| Brinker Capital Destinations Trust | 10,256 | 0 | 0 | 0 | For |
Showing the 25 largest of 51 asset managers. See all 51 in the interactive database.
Combines 9 wordings of this item as funds reported it.
61% Approved · of votes cast
Description as filed by funds: To approve, on an advisory (non- binding) basis, the compensation of the named executive officers as disclosed in the Company's proxy statement for the 2025 Annual Meeting of Stockholders pursuant to the applicable compensation disclosure rules of the SEC, including the compensation tables and narrative discussion.
PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“3. Advisory Vote on Executive Compensation”): 10,671,320 for, 6,919,705 against — passed, per its Form 8-K filed June 27, 2025 (Item 5.07).
Reported outcome: Approved, in the filing’s own words: “Proposal 3 – Advisory Vote on Executive Compensation The Company's stockholders approved, on an advisory (non-binding) basis, the compensation of the Company's named executive officers, with the votes cast as follows:”
Support: 61% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.
Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| Vanguard | 0 | 1,053,731 | 0 | 0 | Against |
| T. Rowe Price | 0 | 905,205 | 0 | 0 | Against |
| BlackRock | 8,223 | 444,535 | 0 | 0 | Against |
| Fidelity | 0 | 397,267 | 0 | 0 | Against |
| State Street | 276,907 | 353 | 0 | 0 | For |
| JANUS INVESTMENT FUND | 234,406 | 0 | 0 | 0 | For |
| Aberdeen | 0 | 150,691 | 0 | 0 | Against |
| Charles Schwab | 0 | 142,945 | 0 | 0 | Against |
| FRANKLIN STRATEGIC SERIES | 0 | 113,704 | 0 | 0 | Against |
| Northern Trust | 0 | 62,824 | 0 | 0 | Against |
| Equitable | 0 | 53,477 | 0 | 0 | Against |
| DRIEHAUS MUTUAL FUNDS | 44,110 | 0 | 0 | 0 | For |
| TIAA | 0 | 43,460 | 0 | 0 | Against |
| Brighthouse | 0 | 41,344 | 1,670 | 0 | Against |
| QUANTITATIVE MASTER SERIES LLC | 0 | 25,976 | 0 | 0 | Against |
| Transamerica | 0 | 20,311 | 0 | 0 | Against |
| RBB FUND, INC. | 19,393 | 0 | 0 | 0 | For |
| ALPS ETF Trust | 0 | 14,808 | 0 | 0 | Against |
| Lincoln Financial | 12,800 | 0 | 0 | 0 | For |
| John Hancock | 0 | 11,969 | 0 | 0 | Against |
| Direxion Shares ETF Trust | 0 | 11,037 | 0 | 0 | Against |
| HUSSMAN INVESTMENT TRUST | 0 | 10,500 | 0 | 0 | Against |
| Global X | 0 | 10,448 | 0 | 0 | Against |
| UBS | 0 | 10,400 | 0 | 0 | Against |
| Brinker Capital Destinations Trust | 10,256 | 0 | 0 | 0 | For |
Fund voting reports, all 52 managers: 611,860 for, 3,576,085 against, 1,670 abstained. Showing the 25 largest; see all in the interactive database.
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,914,591 | 0 | 0 | 0 | For |
| Janus Henderson | 1,431,878 | 34,015 | 0 | 0 | For |
| Cormorant Asset Management, LP | 1,446,372 | 0 | 0 | 0 | For |
| Soleus Capital Management, L.P. | 1,249,740 | 0 | 0 | 0 | For |
| T. Rowe Price | 0 | 1,205,913 | 0 | 0 | Against |
| PERCEPTIVE ADVISORS LLC | 1,093,950 | 0 | 0 | 0 | For |
| BAKER BROS. ADVISORS LP | 689,488 | 0 | 0 | 0 | For |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 686,931 | 0 | 0 | 0 | For |
| State Street | 579,274 | 7,372 | 0 | 0 | For |
| BlackRock | 20,732 | 469,796 | 0 | 0 | Against |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 403,082 | 0 | 0 | Against |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 397,994 | 0 | 0 | 0 | For |
| Point72 | 0 | 370,817 | 0 | 0 | Against |
| CIBC Asset Management Inc | 0 | 336,392 | 0 | 0 | Against |
| FRANKLIN ADVISERS INC | 0 | 314,103 | 0 | 0 | Against |
| VR Adviser, LLC | 244,858 | 0 | 0 | 0 | For |
| Verition Fund Management LLC | 0 | 199,642 | 0 | 0 | Against |
| 5AM Venture Management, LLC | 170,000 | 0 | 0 | 0 | For |
| Aberdeen | 0 | 150,691 | 0 | 0 | Against |
| Charles Schwab | 0 | 142,945 | 0 | 0 | Against |
| Northern Trust | 0 | 128,510 | 0 | 0 | Against |
| PFM Health Sciences, LP | 0 | 126,025 | 0 | 0 | Against |
| Alyeska Investment Group, L.P. | 0 | 107,387 | 0 | 0 | Against |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | 80,793 | 0 | 0 | Against |
| Ally Bridge Group (NY) LLC | 74,327 | 0 | 0 | 0 | For |
Institutional-manager reports, all 151 managers: 10,339,119 for, 4,779,464 against, 21 not voted. Showing the 25 largest; see all in the interactive database.
Combines 2 wordings of this item as funds reported it.
99.9% Approved · of votes cast
Description as filed by funds: TO RATIFY THE SELECTION OF ERNST & YOUNG LLP AS THE COMPANY'S INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR THE FISCAL YEAR ENDING DECEMBER 31, 2025.
PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“2. Ratification of Appointment of Ernst & Young LLP as the Company's Independent Registered Public Accounting Firm”): 18,358,636 for, 7,630 against — passed, per its Form 8-K filed June 27, 2025 (Item 5.07).
Reported outcome: Approved, in the filing’s own words: “Proposal 2 – Ratification of Appointment of Ernst & Young LLP as the Company's Independent Registered Public Accounting Firm The Company's stockholders ratified the appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31…”
Support: 99.9% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.
The 52 asset managers below reported 4,187,945 for, 1,670 abstained.
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| Vanguard | 1,053,731 | 0 | 0 | 0 | For |
| T. Rowe Price | 905,205 | 0 | 0 | 0 | For |
| BlackRock | 452,758 | 0 | 0 | 0 | For |
| Fidelity | 397,267 | 0 | 0 | 0 | For |
| State Street | 277,260 | 0 | 0 | 0 | For |
| JANUS INVESTMENT FUND | 234,406 | 0 | 0 | 0 | For |
| Aberdeen | 150,691 | 0 | 0 | 0 | For |
| Charles Schwab | 142,945 | 0 | 0 | 0 | For |
| FRANKLIN STRATEGIC SERIES | 113,704 | 0 | 0 | 0 | For |
| Northern Trust | 62,824 | 0 | 0 | 0 | For |
| Equitable | 53,477 | 0 | 0 | 0 | For |
| DRIEHAUS MUTUAL FUNDS | 44,110 | 0 | 0 | 0 | For |
| TIAA | 43,460 | 0 | 0 | 0 | For |
| Brighthouse | 41,344 | 0 | 1,670 | 0 | For |
| QUANTITATIVE MASTER SERIES LLC | 25,976 | 0 | 0 | 0 | For |
| Transamerica | 20,311 | 0 | 0 | 0 | For |
| RBB FUND, INC. | 19,393 | 0 | 0 | 0 | For |
| ALPS ETF Trust | 14,808 | 0 | 0 | 0 | For |
| Lincoln Financial | 12,800 | 0 | 0 | 0 | For |
| John Hancock | 11,969 | 0 | 0 | 0 | For |
| Direxion Shares ETF Trust | 11,037 | 0 | 0 | 0 | For |
| HUSSMAN INVESTMENT TRUST | 10,500 | 0 | 0 | 0 | For |
| Global X | 10,448 | 0 | 0 | 0 | For |
| UBS | 10,400 | 0 | 0 | 0 | For |
| Brinker Capital Destinations Trust | 10,256 | 0 | 0 | 0 | For |
Showing the 25 largest of 52 asset managers. See all 52 in the interactive database.
Ranked separately for each type of Form N-PX report. An institutional manager can report shares that a fund it advises also reports, so the two tables can list the same shares and are never added together. Each is ranked by the shares voted on the item that the most managers of that type reported, shown as a share of the 20,341,917 shares outstanding at the time of that meeting.
| # | Asset manager | % of shares outstanding |
|---|---|---|
| 1 | Vanguard | 5.18% |
| 2 | T. Rowe Price | 4.45% |
| 3 | BlackRock | 2.23% |
| 4 | Fidelity | 1.95% |
| 5 | State Street | 1.36% |
| 6 | JANUS INVESTMENT FUND | 1.15% |
| 7 | Aberdeen | 0.74% |
| 8 | Charles Schwab | 0.70% |
| 9 | FRANKLIN STRATEGIC SERIES | 0.56% |
| 10 | Northern Trust | 0.31% |
| # | Asset manager | % of shares outstanding |
|---|---|---|
| 1 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 9.41% |
| 2 | Janus Henderson | 7.21% |
| 3 | Cormorant Asset Management, LP | 7.11% |
| 4 | Soleus Capital Management, L.P. | 6.14% |
| 5 | T. Rowe Price | 5.93% |
| 6 | PERCEPTIVE ADVISORS LLC | 5.38% |
| 7 | BAKER BROS. ADVISORS LP | 3.39% |
| 8 | DEERFIELD MANAGEMENT COMPANY, L.P. | 3.38% |
| 9 | State Street | 2.88% |
| 10 | BlackRock | 2.41% |
As disclosed to the SEC in Form 13F (quarter-end holdings of 30 large managers), Schedules 13D and 13G (beneficial ownership above 5%) and the company’s own proxy statement (DEF 14A). Each row names its form.
| Holder | % outstanding | Disclosure |
|---|---|---|
| JANUS HENDERSON GROUP PLC | 13.59% | 13G |
| ORBIS INVESTMENT MANAGEMENT LTD | 12.13% | 13G |
| FMR LLC | 10.60% | 13G |
| Perceptive Advisors LLC | 9.81% | 13G |
| Entities affiliated with Perceptive Advisors | 8.99% | DEF14A |
| Baker Bros. Advisors LP | 8.62% | 13G |
| BlackRock | 6.97% | 13F |
| Entities affiliated with Point72 | 6.14% | DEF14A |
| Morgan Stanley | 5.97% | 13F |
| Steven A. Cohen | 5.96% | 13G |
Percentages above are of 20,341,917 shares outstanding, as reported by PRAXIS PRECISION MEDICINES INC. on its Form 10-Q dated March 31, 2025 (see the filing on EDGAR). This is the count contemporaneous with the 2024-2025 meeting, not today’s. Each holding is as of its own filing, which may be dated before or after the meeting.
Every figure above is derived from filings made with the US Securities and Exchange Commission: Form N-PX, in which registered funds disclose how they voted every proxy and institutional managers disclose their votes on executive pay (say-on-pay, say-on-frequency and golden parachutes), and Form 8-K Item 5.07, in which the company reports its own meeting results. Shares outstanding are taken from PRAXIS PRECISION MEDICINES INC.’s 10-Q dated March 31, 2025. This page is a static snapshot rebuilt weekly on October 18, 2026; a live search always shows the current data.
At PRAXIS PRECISION MEDICINES INC.'s shareholder meeting held June 26, 2025, in the 2024-2025 proxy season, 188 asset managers reported how they voted on 4 ballot items in their SEC Form N-PX filings, covering 776 separate fund positions. On the most widely held item on that ballot — To approve, on an advisory (non- binding) basis, the compensation of the named executive… — PRAXIS PRECISION MEDICINES INC.'s filing reports the proposal as approved, with 61% support of the votes cast (FOR divided by FOR plus AGAINST, the conventional basis for proxy support; abstentions, broker non-votes and unvoted shares are excluded because none of them took a side). Source: PRAXIS PRECISION MEDICINES INC.'s Form 8-K, Item 5.07, filed with the U.S. Securities and Exchange Commission on June 27, 2025.
PRAXIS PRECISION MEDICINES INC. proxy season coverage: 2024-2025 (this page) · 2025-2026.
Download data (CSV): ballot items · votes by manager · column guide.