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PRAXIS PRECISION MEDICINES INC. 2024-2025 Proxy Voting Records

Compiled from SEC Form N-PX filings and PRAXIS PRECISION MEDICINES INC.’s Form 8-K, filed June 27, 2025 (Item 5.07 on EDGAR). Page generated October 18, 2026.

  • 4Ballot items
  • 188Asset managers
  • 776Fund votes
  • June 26, 2025Meeting date

Results at a glance

Meeting of June 26, 2025: 4 items on PRAXIS PRECISION MEDICINES INC.’s Form 8-K, filed June 27, 2025: 2 approved · 2 without a stated outcome.

Material dissent

Material dissent: a director nominee under 80% of the votes cast, say-on-pay under 70%, any other item the board put forward under 80%, or a shareholder proposal with more than 50%, on the company’s own Form 8-K tally. How this is decided

Proxy season: 2024-2025 2025-2026

Explore PRAXIS PRECISION MEDICINES INC. in the interactive database Compare manager voting policies

Official 2024-2025 meeting results reported by PRAXIS PRECISION MEDICINES INC.

These tallies are PRAXIS PRECISION MEDICINES INC.’s own, as disclosed to the U.S. Securities and Exchange Commission on Form 8-K, filed June 27, 2025 (Item 5.07, “Submission of Matters to a Vote of Security Holders”). They cover every share voted at the meeting, not just the funds that file Form N-PX.

PRAXIS PRECISION MEDICINES INC. — official shareholder meeting results, meeting held June 26, 2025
Ballot itemForAgainst AbstainWithheldBroker non-votesSupport (of votes cast)Reported outcomeVoting standard
Elect Director: Jeffrey Chodakewitz, M.D. 14,596,188---- 2,998,186778,152 83%Not verified—
Elect Director: Merit Cudkowicz, M.D. 17,499,300---- 95,074778,152 99.4%Not verified—
2. Ratification of Appointment of Ernst & Young LLP as the Company's Independent Registered Public Accounting Firm 18,358,6367,6306,260 --0 99.9%Approved—
3. Advisory Vote on Executive Compensation 10,671,3206,919,7053,349 --778,152 61%Approved—

Source: PRAXIS PRECISION MEDICINES INC., Form 8-K, filed with the SEC on June 27, 2025 — read the filing on EDGAR.

How asset managers voted at the PRAXIS PRECISION MEDICINES INC. 2024-2025 meeting

Each item below shows how the 188 asset managers that disclosed a PRAXIS PRECISION MEDICINES INC. vote in their SEC Form N-PX filings actually voted. Share totals are the shares those managers' funds voted, summed across every fund they report.

1. Elect Director: Jeffrey Chodakewitz, M.D.

Outcome not verifiedDIRECTOR ELECTIONSReported outcome: Not verified

Combines 3 wordings of this item as funds reported it.

83% Majority: yes · of votes cast

FOR 83%WITHHELD
FOR: 14,596,188WITHHELD: 2,998,186
Details: description as filed, official tally, votes by 51 asset managers

Description as filed by funds: To elect the Class II Directors to serve until the 2028 Annual Meeting of Stockholders and until their respective successors have been duly elected and qualified: Jeffrey Chodakewitz, M.D.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“Elect Director: Jeffrey Chodakewitz, M.D.”): 14,596,188 for, 2,998,186 withheld, per its Form 8-K filed June 27, 2025 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.

Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 83% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.

The 51 asset managers below reported 3,712,298 for, 477,120 withheld.

FOR
FOR: 3,712,298WITHHOLD: 477,120
Largest asset managers voting on “To elect the Class II Directors to serve until the 2028 Annual Meeting of Stockholders and until their respect” at PRAXIS PRECISION MEDICINES INC., 2024-2025
Asset managerForAgainst AbstainWithheldVote
Vanguard1,053,7310 00For
T. Rowe Price905,2050 00For
BlackRock452,7580 00For
Fidelity361,3980 035,869Mixed
State Street276,9070 0353For
JANUS INVESTMENT FUND234,4060 00For
Aberdeen00 0150,691Withhold
Charles Schwab142,9450 00For
FRANKLIN STRATEGIC SERIES00 0113,704Withhold
Northern Trust00 062,824Withhold
Equitable35,4370 018,040Mixed
DRIEHAUS MUTUAL FUNDS44,1100 00For
TIAA43,4600 00For
Brighthouse35,0920 07,922Mixed
QUANTITATIVE MASTER SERIES LLC25,9760 00For
Transamerica20,3110 00For
RBB FUND, INC.19,3930 00For
ALPS ETF Trust00 014,808Withhold
Lincoln Financial12,8000 00For
John Hancock5,8320 06,137Mixed
Direxion Shares ETF Trust00 011,037Withhold
HUSSMAN INVESTMENT TRUST10,5000 00For
Global X00 010,448Withhold
UBS00 010,400Withhold
Brinker Capital Destinations Trust10,2560 00For

Showing the 25 largest of 51 asset managers. See all 51 in the interactive database.

2. Elect Director: Merit Cudkowicz, M.D.

Outcome not verifiedDIRECTOR ELECTIONSReported outcome: Not verified

Combines 3 wordings of this item as funds reported it.

99.4% Majority: yes · of votes cast

FOR 99.4%
FOR: 17,499,300WITHHELD: 95,074
Details: description as filed, official tally, votes by 51 asset managers

Description as filed by funds: To elect the Class II Directors to serve until the 2028 Annual Meeting of Stockholders and until their respective successors have been duly elected and qualified: Merit Cudkowicz, M.D.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“Elect Director: Merit Cudkowicz, M.D.”): 17,499,300 for, 95,074 withheld, per its Form 8-K filed June 27, 2025 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.

Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 99.4% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.

The 51 asset managers below reported 4,150,190 for, 39,228 withheld.

FOR
FOR: 4,150,190WITHHOLD: 39,228
Largest asset managers voting on “To elect the Class II Directors to serve until the 2028 Annual Meeting of Stockholders and until their respect” at PRAXIS PRECISION MEDICINES INC., 2024-2025
Asset managerForAgainst AbstainWithheldVote
Vanguard1,053,7310 00For
T. Rowe Price905,2050 00For
BlackRock452,7580 00For
Fidelity361,3980 035,869Mixed
State Street277,2600 00For
JANUS INVESTMENT FUND234,4060 00For
Aberdeen150,6910 00For
Charles Schwab142,9450 00For
FRANKLIN STRATEGIC SERIES113,7040 00For
Northern Trust62,8240 00For
Equitable53,4770 00For
DRIEHAUS MUTUAL FUNDS44,1100 00For
TIAA43,4600 00For
Brighthouse41,3440 01,670For
QUANTITATIVE MASTER SERIES LLC25,9760 00For
Transamerica20,3110 00For
RBB FUND, INC.19,3930 00For
ALPS ETF Trust14,8080 00For
Lincoln Financial12,8000 00For
John Hancock11,9690 00For
Direxion Shares ETF Trust11,0370 00For
HUSSMAN INVESTMENT TRUST10,5000 00For
Global X10,4480 00For
UBS10,4000 00For
Brinker Capital Destinations Trust10,2560 00For

Showing the 25 largest of 51 asset managers. See all 51 in the interactive database.

3. 3. Advisory Vote on Executive Compensation

Official resultFund totals may overlapSECTION 14A SAY-ON-PAY VOTESReported outcome: Approved

Combines 9 wordings of this item as funds reported it.

61% Approved · of votes cast

FOR 61%AGAINST
FOR: 10,671,320AGAINST: 6,919,705
Details: description as filed, official tally, votes by 188 asset managers

Description as filed by funds: To approve, on an advisory (non- binding) basis, the compensation of the named executive officers as disclosed in the Company's proxy statement for the 2025 Annual Meeting of Stockholders pursuant to the applicable compensation disclosure rules of the SEC, including the compensation tables and narrative discussion.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“3. Advisory Vote on Executive Compensation”): 10,671,320 for, 6,919,705 against — passed, per its Form 8-K filed June 27, 2025 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 3 – Advisory Vote on Executive Compensation The Company's stockholders approved, on an advisory (non-binding) basis, the compensation of the Company's named executive officers, with the votes cast as follows:”
Support: 61% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).

Fund voting reports: 52 asset managers voting on “To approve, on an advisory (non- binding) basis, the compensation of the named executive officers as disclosed” at PRAXIS PRECISION MEDICINES INC., 2024-2025
Asset managerForAgainst AbstainWithheldVote
Vanguard01,053,731 00Against
T. Rowe Price0905,205 00Against
BlackRock8,223444,535 00Against
Fidelity0397,267 00Against
State Street276,907353 00For
JANUS INVESTMENT FUND234,4060 00For
Aberdeen0150,691 00Against
Charles Schwab0142,945 00Against
FRANKLIN STRATEGIC SERIES0113,704 00Against
Northern Trust062,824 00Against
Equitable053,477 00Against
DRIEHAUS MUTUAL FUNDS44,1100 00For
TIAA043,460 00Against
Brighthouse041,344 1,6700Against
QUANTITATIVE MASTER SERIES LLC025,976 00Against
Transamerica020,311 00Against
RBB FUND, INC.19,3930 00For
ALPS ETF Trust014,808 00Against
Lincoln Financial12,8000 00For
John Hancock011,969 00Against
Direxion Shares ETF Trust011,037 00Against
HUSSMAN INVESTMENT TRUST010,500 00Against
Global X010,448 00Against
UBS010,400 00Against
Brinker Capital Destinations Trust10,2560 00For

Fund voting reports, all 52 managers: 611,860 for, 3,576,085 against, 1,670 abstained. Showing the 25 largest; see all in the interactive database.

Institutional-manager reports: 151 asset managers voting on “To approve, on an advisory (non- binding) basis, the compensation of the named executive officers as disclosed” at PRAXIS PRECISION MEDICINES INC., 2024-2025
Asset managerForAgainst AbstainWithheldVote
ADAGE CAPITAL PARTNERS GP, L.L.C.1,914,5910 00For
Janus Henderson1,431,87834,015 00For
Cormorant Asset Management, LP1,446,3720 00For
Soleus Capital Management, L.P.1,249,7400 00For
T. Rowe Price01,205,913 00Against
PERCEPTIVE ADVISORS LLC1,093,9500 00For
BAKER BROS. ADVISORS LP689,4880 00For
DEERFIELD MANAGEMENT COMPANY, L.P.686,9310 00For
State Street579,2747,372 00For
BlackRock20,732469,796 00Against
GEODE CAPITAL MANAGEMENT, LLC0403,082 00Against
DRIEHAUS CAPITAL MANAGEMENT LLC397,9940 00For
Point720370,817 00Against
CIBC Asset Management Inc0336,392 00Against
FRANKLIN ADVISERS INC0314,103 00Against
VR Adviser, LLC244,8580 00For
Verition Fund Management LLC0199,642 00Against
5AM Venture Management, LLC170,0000 00For
Aberdeen0150,691 00Against
Charles Schwab0142,945 00Against
Northern Trust0128,510 00Against
PFM Health Sciences, LP0126,025 00Against
Alyeska Investment Group, L.P.0107,387 00Against
SILVERARC CAPITAL MANAGEMENT, LLC080,793 00Against
Ally Bridge Group (NY) LLC74,3270 00For

Institutional-manager reports, all 151 managers: 10,339,119 for, 4,779,464 against, 21 not voted. Showing the 25 largest; see all in the interactive database.

4. 2. Ratification of Appointment of Ernst & Young LLP as the Company's Independent Registered Public Accounting Firm

Official resultAUDIT-RELATEDReported outcome: Approved

Combines 2 wordings of this item as funds reported it.

99.9% Approved · of votes cast

FOR 99.9%
FOR: 18,358,636AGAINST: 7,630
Details: description as filed, official tally, votes by 52 asset managers

Description as filed by funds: TO RATIFY THE SELECTION OF ERNST & YOUNG LLP AS THE COMPANY'S INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR THE FISCAL YEAR ENDING DECEMBER 31, 2025.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“2. Ratification of Appointment of Ernst & Young LLP as the Company's Independent Registered Public Accounting Firm”): 18,358,636 for, 7,630 against — passed, per its Form 8-K filed June 27, 2025 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 2 – Ratification of Appointment of Ernst & Young LLP as the Company's Independent Registered Public Accounting Firm The Company's stockholders ratified the appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31…”
Support: 99.9% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

The 52 asset managers below reported 4,187,945 for, 1,670 abstained.

FOR
FOR: 4,187,945ABSTAIN: 1,670
Largest asset managers voting on “TO RATIFY THE SELECTION OF ERNST & YOUNG LLP AS THE COMPANY'S INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FO” at PRAXIS PRECISION MEDICINES INC., 2024-2025
Asset managerForAgainst AbstainWithheldVote
Vanguard1,053,7310 00For
T. Rowe Price905,2050 00For
BlackRock452,7580 00For
Fidelity397,2670 00For
State Street277,2600 00For
JANUS INVESTMENT FUND234,4060 00For
Aberdeen150,6910 00For
Charles Schwab142,9450 00For
FRANKLIN STRATEGIC SERIES113,7040 00For
Northern Trust62,8240 00For
Equitable53,4770 00For
DRIEHAUS MUTUAL FUNDS44,1100 00For
TIAA43,4600 00For
Brighthouse41,3440 1,6700For
QUANTITATIVE MASTER SERIES LLC25,9760 00For
Transamerica20,3110 00For
RBB FUND, INC.19,3930 00For
ALPS ETF Trust14,8080 00For
Lincoln Financial12,8000 00For
John Hancock11,9690 00For
Direxion Shares ETF Trust11,0370 00For
HUSSMAN INVESTMENT TRUST10,5000 00For
Global X10,4480 00For
UBS10,4000 00For
Brinker Capital Destinations Trust10,2560 00For

Showing the 25 largest of 52 asset managers. See all 52 in the interactive database.

Largest PRAXIS PRECISION MEDICINES INC. shareholders voting in 2024-2025

Ranked separately for each type of Form N-PX report. An institutional manager can report shares that a fund it advises also reports, so the two tables can list the same shares and are never added together. Each is ranked by the shares voted on the item that the most managers of that type reported, shown as a share of the 20,341,917 shares outstanding at the time of that meeting.

Fund voting reports: top PRAXIS PRECISION MEDICINES INC. shareholders by shares voted on “To approve, on an advisory (non- binding) basis, the compensation of the named executive…”, 2024-2025
#Asset manager % of shares outstanding
1Vanguard 5.18%
2T. Rowe Price 4.45%
3BlackRock 2.23%
4Fidelity 1.95%
5State Street 1.36%
6JANUS INVESTMENT FUND 1.15%
7Aberdeen 0.74%
8Charles Schwab 0.70%
9FRANKLIN STRATEGIC SERIES 0.56%
10Northern Trust 0.31%
Institutional-manager reports: top PRAXIS PRECISION MEDICINES INC. shareholders by shares voted on “To approve, on an advisory (non- binding) basis, the compensation of the named executive…”, 2024-2025
#Asset manager % of shares outstanding
1ADAGE CAPITAL PARTNERS GP, L.L.C. 9.41%
2Janus Henderson 7.21%
3Cormorant Asset Management, LP 7.11%
4Soleus Capital Management, L.P. 6.14%
5T. Rowe Price 5.93%
6PERCEPTIVE ADVISORS LLC 5.38%
7BAKER BROS. ADVISORS LP 3.39%
8DEERFIELD MANAGEMENT COMPANY, L.P. 3.38%
9State Street 2.88%
10BlackRock 2.41%

Reported PRAXIS PRECISION MEDICINES INC. holdings and ownership

As disclosed to the SEC in Form 13F (quarter-end holdings of 30 large managers), Schedules 13D and 13G (beneficial ownership above 5%) and the company’s own proxy statement (DEF 14A). Each row names its form.

PRAXIS PRECISION MEDICINES INC. holdings and ownership disclosed for the 2024-2025 proxy season
Holder % outstanding Disclosure
JANUS HENDERSON GROUP PLC 13.59% 13G
ORBIS INVESTMENT MANAGEMENT LTD 12.13% 13G
FMR LLC 10.60% 13G
Perceptive Advisors LLC 9.81% 13G
Entities affiliated with Perceptive Advisors 8.99% DEF14A
Baker Bros. Advisors LP 8.62% 13G
BlackRock 6.97% 13F
Entities affiliated with Point72 6.14% DEF14A
Morgan Stanley 5.97% 13F
Steven A. Cohen 5.96% 13G

Percentages above are of 20,341,917 shares outstanding, as reported by PRAXIS PRECISION MEDICINES INC. on its Form 10-Q dated March 31, 2025 (see the filing on EDGAR). This is the count contemporaneous with the 2024-2025 meeting, not today’s. Each holding is as of its own filing, which may be dated before or after the meeting.

About this page

Every figure above is derived from filings made with the US Securities and Exchange Commission: Form N-PX, in which registered funds disclose how they voted every proxy and institutional managers disclose their votes on executive pay (say-on-pay, say-on-frequency and golden parachutes), and Form 8-K Item 5.07, in which the company reports its own meeting results. Shares outstanding are taken from PRAXIS PRECISION MEDICINES INC.’s 10-Q dated March 31, 2025. This page is a static snapshot rebuilt weekly on October 18, 2026; a live search always shows the current data.

At PRAXIS PRECISION MEDICINES INC.'s shareholder meeting held June 26, 2025, in the 2024-2025 proxy season, 188 asset managers reported how they voted on 4 ballot items in their SEC Form N-PX filings, covering 776 separate fund positions. On the most widely held item on that ballot — To approve, on an advisory (non- binding) basis, the compensation of the named executive… — PRAXIS PRECISION MEDICINES INC.'s filing reports the proposal as approved, with 61% support of the votes cast (FOR divided by FOR plus AGAINST, the conventional basis for proxy support; abstentions, broker non-votes and unvoted shares are excluded because none of them took a side). Source: PRAXIS PRECISION MEDICINES INC.'s Form 8-K, Item 5.07, filed with the U.S. Securities and Exchange Commission on June 27, 2025.

PRAXIS PRECISION MEDICINES INC. proxy season coverage: 2024-2025 (this page) · 2025-2026.

Download data (CSV): ballot items · votes by manager · column guide.