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Denali Therapeutics Inc. 2025-2026 Proxy Voting Records

Compiled from SEC Form N-PX filings and Denali Therapeutics Inc.’s Form 8-K, filed June 4, 2026 (Item 5.07 on EDGAR). Page generated October 25, 2026.

  • 5Ballot items
  • 278Asset managers
  • 1,656Fund votes
  • June 3, 2026Meeting date

Results at a glance

Meeting of June 3, 2026: 5 items on Denali Therapeutics Inc.’s Form 8-K, filed June 4, 2026: 3 elected · 2 approved.

Material dissent

Material dissent: a director nominee under 80% of the votes cast, say-on-pay under 70%, any other item the board put forward under 80%, or a shareholder proposal with more than 50%, on the company’s own Form 8-K tally. How this is decided

Proxy season: 2023-2024 2024-2025 2025-2026

Explore Denali Therapeutics Inc. in the interactive database Compare manager voting policies

Official 2025-2026 meeting results reported by Denali Therapeutics Inc.

These tallies are Denali Therapeutics Inc.’s own, as disclosed to the U.S. Securities and Exchange Commission on Form 8-K, filed June 4, 2026 (Item 5.07, “Submission of Matters to a Vote of Security Holders”). They cover every share voted at the meeting, not just the funds that file Form N-PX.

Denali Therapeutics Inc. — official shareholder meeting results, meeting held June 3, 2026
Ballot itemForAgainst AbstainWithheldBroker non-votesSupport (of votes cast)Reported outcomeVoting standard
Elect Director: Jennifer Cook 75,998,259---- 48,847,02913,140,839 61%Elected—
Elect Director: David Schenkein, M.D. 91,814,688---- 33,030,60013,140,839 74%Elected—
Elect Director: Ryan Watts, Ph.D. 121,220,572---- 3,624,71613,140,839 97%Elected—
2. Ratification of Appointment of Independent Registered Public Accounting Firm The appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2026 137,516,267420,30549,555 ---- 99.6%Approved—
3. Advisory Vote to Approve Executive Compensation 117,038,7457,088,810717,733 --13,140,839 94%Approved—

Source: Denali Therapeutics Inc., Form 8-K, filed with the SEC on June 4, 2026 — read the filing on EDGAR.

How asset managers voted at the Denali Therapeutics Inc. 2025-2026 meeting

Each item below shows how the 278 asset managers that disclosed a Denali Therapeutics Inc. vote in their SEC Form N-PX filings actually voted. Share totals are the shares those managers' funds voted, summed across every fund they report.

1. Elect Director: David Schenkein, M.D.

Official resultDIRECTOR ELECTIONSReported outcome: Elected

Combines 6 wordings of this item as funds reported it.

74% Majority: yes · of votes cast

FOR 74%WITHHELD
FOR: 91,814,688WITHHELD: 33,030,600
Details: description as filed, official tally, votes by 70 asset managers

Description as filed by funds: ELECTION OF DIRECTORS: David Schenkein, M.D.

Denali Therapeutics Inc.’s own tally for this item (“Elect Director: David Schenkein, M.D.”): 91,814,688 for, 33,030,600 withheld, per its Form 8-K filed June 4, 2026 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.

Reported outcome: Elected, in the filing’s own words: “Each of the following nominees was elected to serve as a Class III director, to hold office until the Company's 2029 annual meeting of stockholders or until his or her respective successor has been duly elected and qualified or his or her earlier resignation or removal.”
Support: 74% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.

The 70 asset managers below reported 37,281,142 for, 10,478,120 withheld, 311,495 abstained.

FORWITHHOLD
FOR: 37,281,142ABSTAIN: 311,495WITHHOLD: 10,478,120
Largest asset managers voting on “ELECTION OF DIRECTORS: David Schenkein, M.D.” at Denali Therapeutics Inc., 2025-2026
Asset managerForAgainst AbstainWithheldVote
Vanguard15,259,1970 870For
T. Rowe Price1,705,1630 05,207,668Mixed
Fidelity5,767,4050 00For
BlackRock5,584,1770 00For
Capital Group2,687,6840 00For
State Street2,401,4850 02,712For
Charles Schwab1,207,1650 00For
AllianceBernstein00 0895,718Withhold
Principal00 0792,720Withhold
Dimensional00 0752,453Withhold
Goldman Sachs694,6270 00For
American Century00 0660,212Withhold
AB DISCOVERY GROWTH FUND, INC.00 0608,609Withhold
Equitable212,4300 0333,761Mixed
TIAA278,4500 00For
QUANTITATIVE MASTER SERIES LLC230,7040 00For
Jackson National00 178,8120Abstain
Brighthouse70,8980 091,426Mixed
BNY Mellon156,3610 05,106For
Lincoln Financial101,4230 051,347Mixed
JPMorgan138,9600 00For
Segall Bryant & Hamill Trust00 0138,028Withhold
Invesco121,8910 00For
OPTIMUM FUND TRUST00 0114,524Withhold
ALPS ETF Trust00 0110,155Withhold

Showing the 25 largest of 70 asset managers. See all 70 in the interactive database.

2. Elect Director: Jennifer Cook

Official resultDIRECTOR ELECTIONSReported outcome: Elected

Combines 6 wordings of this item as funds reported it.

61% Majority: yes · of votes cast

FOR 61%WITHHELD
FOR: 75,998,259WITHHELD: 48,847,029
Details: description as filed, official tally, votes by 70 asset managers

Description as filed by funds: ELECTION OF DIRECTORS: Jennifer Cook

Denali Therapeutics Inc.’s own tally for this item (“Elect Director: Jennifer Cook”): 75,998,259 for, 48,847,029 withheld, per its Form 8-K filed June 4, 2026 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.

Reported outcome: Elected, in the filing’s own words: “Each of the following nominees was elected to serve as a Class III director, to hold office until the Company's 2029 annual meeting of stockholders or until his or her respective successor has been duly elected and qualified or his or her earlier resignation or removal.”
Support: 61% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.

The 70 asset managers below reported 28,911,364 for, 13,528,808 withheld, 5,630,585 abstained.

FORWITHHOLD
FOR: 28,911,364ABSTAIN: 5,630,585WITHHOLD: 13,528,808
Largest asset managers voting on “ELECTION OF DIRECTORS: Jennifer Cook” at Denali Therapeutics Inc., 2025-2026
Asset managerForAgainst AbstainWithheldVote
Vanguard15,251,2940 1057,885For
T. Rowe Price1,705,1630 05,207,668Mixed
Fidelity5,705,2700 062,135For
BlackRock558,1680 5,026,0090Mixed
Capital Group2,687,6840 00For
State Street4,7880 02,399,409Withhold
Charles Schwab1,207,1650 00For
AllianceBernstein00 0895,718Withhold
Principal00 0792,720Withhold
Dimensional00 0752,453Withhold
Goldman Sachs694,6270 00For
American Century00 0660,212Withhold
AB DISCOVERY GROWTH FUND, INC.00 0608,609Withhold
Equitable8,6980 0537,493Withhold
TIAA278,4500 00For
QUANTITATIVE MASTER SERIES LLC00 230,7040Abstain
Jackson National00 178,8120Abstain
Brighthouse70,8980 091,426Mixed
BNY Mellon156,3610 05,106For
Lincoln Financial12,0230 0140,747Mixed
JPMorgan138,9600 00For
Segall Bryant & Hamill Trust00 0138,028Withhold
Invesco121,8910 00For
OPTIMUM FUND TRUST00 0114,524Withhold
ALPS ETF Trust00 0110,155Withhold

Showing the 25 largest of 70 asset managers. See all 70 in the interactive database.

3. Elect Director: Ryan Watts, Ph.D.

Official resultDIRECTOR ELECTIONSReported outcome: Elected

Combines 6 wordings of this item as funds reported it.

97% Majority: yes · of votes cast

FOR 97%
FOR: 121,220,572WITHHELD: 3,624,716
Details: description as filed, official tally, votes by 70 asset managers

Description as filed by funds: ELECTION OF DIRECTORS: Ryan Watts, Ph.D.

Denali Therapeutics Inc.’s own tally for this item (“Elect Director: Ryan Watts, Ph.D.”): 121,220,572 for, 3,624,716 withheld, per its Form 8-K filed June 4, 2026 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.

Reported outcome: Elected, in the filing’s own words: “Each of the following nominees was elected to serve as a Class III director, to hold office until the Company's 2029 annual meeting of stockholders or until his or her respective successor has been duly elected and qualified or his or her earlier resignation or removal.”
Support: 97% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.

The 70 asset managers below reported 47,151,247 for, 844,207 withheld, 75,304 abstained.

FOR
FOR: 47,151,247ABSTAIN: 75,304WITHHOLD: 844,207
Largest asset managers voting on “ELECTION OF DIRECTORS: Ryan Watts, Ph.D.” at Denali Therapeutics Inc., 2025-2026
Asset managerForAgainst AbstainWithheldVote
Vanguard15,259,2740 100For
T. Rowe Price6,912,8310 00For
Fidelity5,767,4050 00For
BlackRock5,584,1770 00For
Capital Group2,687,6840 00For
State Street2,404,1730 024For
Charles Schwab1,207,1650 00For
AllianceBernstein895,7180 00For
Principal792,7200 00For
Dimensional00 0752,453Withhold
Goldman Sachs694,6270 00For
American Century660,2120 00For
AB DISCOVERY GROWTH FUND, INC.608,6090 00For
Equitable546,1910 00For
TIAA278,4500 00For
QUANTITATIVE MASTER SERIES LLC230,7040 00For
Jackson National147,2580 31,5540Mixed
Brighthouse118,4990 043,825Mixed
BNY Mellon161,4670 00For
Lincoln Financial145,3380 07,432For
JPMorgan138,9600 00For
Segall Bryant & Hamill Trust138,0280 00For
Invesco121,8910 00For
OPTIMUM FUND TRUST114,5240 00For
ALPS ETF Trust110,1550 00For

Showing the 25 largest of 70 asset managers. See all 70 in the interactive database.

4. 3. Advisory Vote to Approve Executive Compensation

Official resultFund totals may overlapSECTION 14A SAY-ON-PAY VOTESReported outcome: Approved

Combines 4 wordings of this item as funds reported it.

94% Approved · of votes cast

FOR 94%
FOR: 117,038,745AGAINST: 7,088,810
Details: description as filed, official tally, votes by 278 asset managers

Description as filed by funds: To approve, on an advisory basis, executive compensation.

Denali Therapeutics Inc.’s own tally for this item (“3. Advisory Vote to Approve Executive Compensation”): 117,038,745 for, 7,088,810 against — passed, per its Form 8-K filed June 4, 2026 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 3 - Advisory Vote to Approve Executive Compensation The Company's stockholders approved, on a non-binding, advisory basis, the compensation of the Company's named executive officers as disclosed in the Proxy Statement.”
Support: 94% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).

Fund voting reports: 70 asset managers voting on “To approve, on an advisory basis, executive compensation.” at Denali Therapeutics Inc., 2025-2026
Asset managerForAgainst AbstainWithheldVote
Vanguard15,259,27110 20For
T. Rowe Price6,912,8310 00For
Fidelity5,767,4050 00For
BlackRock5,584,1770 00For
Capital Group02,687,684 00Against
State Street2,404,1970 00For
Charles Schwab1,207,1650 00For
AllianceBernstein895,7180 00For
Principal792,7200 00For
Dimensional752,4530 00For
Goldman Sachs694,6270 00For
American Century0660,212 00Against
AB DISCOVERY GROWTH FUND, INC.608,6090 00For
Equitable546,1910 00For
TIAA278,4500 00For
QUANTITATIVE MASTER SERIES LLC230,7040 00For
Jackson National178,8120 00For
Brighthouse118,4990 43,8250Mixed
BNY Mellon161,4670 00For
Lincoln Financial152,7700 00For
JPMorgan138,9600 00For
Segall Bryant & Hamill Trust138,0280 00For
Invesco121,8910 00For
OPTIMUM FUND TRUST114,5240 00For
ALPS ETF Trust110,1550 00For

Fund voting reports, all 70 managers: 44,679,372 for, 3,347,906 against, 43,827 abstained. Showing the 25 largest; see all in the interactive database.

Institutional-manager reports: 222 asset managers voting on “To approve, on an advisory basis, executive compensation.” at Denali Therapeutics Inc., 2025-2026
Asset managerForAgainst AbstainWithheldVote
T. Rowe Price11,253,9890 00For
BAILLIE GIFFORD & CO LTD8,667,2480 00For
State Street5,290,0250 00For
BlackRock4,842,996164 00For
Fidelity4,531,6500 00For
BAKER BROS. ADVISORS LP3,731,6950 00For
GEODE CAPITAL MANAGEMENT, LLC3,731,1310 00For
BAILLIE GIFFORD OVERSEAS LTD3,040,9540 00For
AllianceBernstein2,745,6340 00For
Capital Research Global Investors02,687,684 00Against
PICTET ASSET MANAGEMENT SA2,402,8810 00For
UBS01,895,335 00Against
Lynx1 Capital Management LP1,880,3030 00For
Aberdeen1,854,4460 00For
Goldman Sachs1,638,5070 00For
Fisher Asset Management, LLC1,491,4310 00For
Siren, L.L.C.1,396,5130 00For
Charles Schwab1,220,2890 00For
Foresite Capital Management VI LLC1,209,9710 00For
Vanguard1,187,1700 00For
Candriam S.C.A.1,099,8450 00For
PRINCIPAL GLOBAL INVESTORS982,0360 00For
Northern Trust956,1500 00For
Vestal Point Capital, LP846,7620 00For
Artisan784,2150 00For

Institutional-manager reports, all 222 managers: 74,897,630 for, 6,063,611 against, 81 abstained, 3,322 not voted. Showing the 25 largest; see all in the interactive database.

5. 2. Ratification of Appointment of Independent Registered Public Accounting Firm The appointment of Ernst & Young LLP as…

Official resultAUDIT-RELATEDReported outcome: Approved

Combines 2 wordings of this item as funds reported it.

99.6% Approved · of votes cast

FOR 99.6%
FOR: 137,516,267AGAINST: 420,305
Details: description as filed, official tally, votes by 71 asset managers

Description as filed by funds: RATIFICATION OF THE APPOINTMENT OF ERNST & YOUNG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR OUR FISCAL YEAR ENDING DECEMBER 31, 2026.

Denali Therapeutics Inc.’s own tally for this item (“2. Ratification of Appointment of Independent Registered Public Accounting Firm The appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, ”): 137,516,267 for, 420,305 against — passed, per its Form 8-K filed June 4, 2026 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 2 - Ratification of Appointment of Independent Registered Public Accounting Firm The appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2026 was ratified based on the following results of voting:”
Support: 99.6% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

The 71 asset managers below reported 48,009,137 for, 18,153 against, 43,825 abstained.

FOR
FOR: 48,009,137AGAINST: 18,153ABSTAIN: 43,825
Largest asset managers voting on “RATIFICATION OF THE APPOINTMENT OF ERNST & YOUNG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR ” at Denali Therapeutics Inc., 2025-2026
Asset managerForAgainst AbstainWithheldVote
Vanguard15,259,2831 00For
T. Rowe Price6,912,8310 00For
Fidelity5,767,4050 00For
BlackRock5,584,1770 00For
Capital Group2,687,6840 00For
State Street2,404,10394 00For
Charles Schwab1,207,1650 00For
AllianceBernstein895,7180 00For
Principal792,7200 00For
Dimensional752,4530 00For
Goldman Sachs694,6270 00For
American Century660,2120 00For
AB DISCOVERY GROWTH FUND, INC.608,6090 00For
Equitable546,1910 00For
TIAA278,4500 00For
QUANTITATIVE MASTER SERIES LLC230,7040 00For
Jackson National178,8120 00For
Brighthouse118,4990 43,8250Mixed
BNY Mellon161,4670 00For
Lincoln Financial152,7700 00For
JPMorgan138,9600 00For
Segall Bryant & Hamill Trust138,0280 00For
Invesco121,8910 00For
OPTIMUM FUND TRUST114,5240 00For
ALPS ETF Trust110,1550 00For

Showing the 25 largest of 71 asset managers. See all 71 in the interactive database.

Largest Denali Therapeutics Inc. shareholders voting in 2025-2026

Ranked separately for each type of Form N-PX report. An institutional manager can report shares that a fund it advises also reports, so the two tables can list the same shares and are never added together. Each is ranked by the shares voted on the item that the most managers of that type reported, shown as a share of the 158,656,318 shares outstanding at the time of that meeting.

Fund voting reports: top Denali Therapeutics Inc. shareholders by shares voted on “To approve, on an advisory basis, executive compensation.”, 2025-2026
#Asset manager % of shares outstanding
1Vanguard 9.62%
2T. Rowe Price 4.36%
3Fidelity 3.64%
4BlackRock 3.52%
5Capital Group 1.69%
6State Street 1.52%
7Charles Schwab 0.76%
8AllianceBernstein 0.56%
9Principal 0.50%
10Dimensional 0.47%
Institutional-manager reports: top Denali Therapeutics Inc. shareholders by shares voted on “To approve, on an advisory basis, executive compensation.”, 2025-2026
#Asset manager % of shares outstanding
1T. Rowe Price 7.09%
2BAILLIE GIFFORD & CO LTD 5.46%
3State Street 3.33%
4BlackRock 3.05%
5Fidelity 2.86%
6BAKER BROS. ADVISORS LP 2.35%
7GEODE CAPITAL MANAGEMENT, LLC 2.35%
8BAILLIE GIFFORD OVERSEAS LTD 1.92%
9AllianceBernstein 1.73%
10Capital Research Global Investors 1.69%

Reported Denali Therapeutics Inc. holdings and ownership

As disclosed to the SEC in Form 13F (quarter-end holdings of 30 large managers), Schedules 13D and 13G (beneficial ownership above 5%) and the company’s own proxy statement (DEF 14A). Each row names its form.

Denali Therapeutics Inc. holdings and ownership disclosed for the 2025-2026 proxy season
Holder % outstanding Disclosure
Vanguard Group 8.23% 13F
BlackRock 8.22% 13F
BAILLIE GIFFORD & CO 7.54% 13G
FMR LLC 5.38% DEF14A
Julian C. Baker 5.13% DEF14A
State Street 3.95% 13F
FMR (Fidelity) 2.88% 13F
Goldman Sachs 2.78% 13F
Ryan J. Watts, Ph.D. 2.68% DEF14A
Geode Capital 2.35% 13F

Percentages above are of 158,656,318 shares outstanding, as reported by Denali Therapeutics Inc. on its Form 10-Q dated March 31, 2026 (see the filing on EDGAR). This is the count contemporaneous with the 2025-2026 meeting, not today’s. Each holding is as of its own filing, which may be dated before or after the meeting.

About this page

Every figure above is derived from filings made with the US Securities and Exchange Commission: Form N-PX, in which registered funds disclose how they voted every proxy and institutional managers disclose their votes on executive pay (say-on-pay, say-on-frequency and golden parachutes), and Form 8-K Item 5.07, in which the company reports its own meeting results. Shares outstanding are taken from Denali Therapeutics Inc.’s 10-Q dated March 31, 2026. This page is a static snapshot rebuilt weekly on October 25, 2026; a live search always shows the current data.

At Denali Therapeutics Inc.'s shareholder meeting held June 3, 2026, in the 2025-2026 proxy season, 278 asset managers reported how they voted on 5 ballot items in their SEC Form N-PX filings, covering 1,656 separate fund positions. On the most widely held item on that ballot — To approve, on an advisory basis, executive compensation. — Denali Therapeutics Inc.'s filing reports the proposal as approved, with 94% support of the votes cast (FOR divided by FOR plus AGAINST, the conventional basis for proxy support; abstentions, broker non-votes and unvoted shares are excluded because none of them took a side). Source: Denali Therapeutics Inc.'s Form 8-K, Item 5.07, filed with the U.S. Securities and Exchange Commission on June 4, 2026.

Denali Therapeutics Inc. proxy season coverage: 2023-2024 · 2024-2025 · 2025-2026 (this page).

Download data (CSV): ballot items · votes by manager · column guide.